The source of synergetic innovation relationship between start-up enterprises is from the application of the social network. Based on the theory of social network, empirical analysis is made about the logical connection between geographical proximity and recognition proximity with the synergetic innovation relationship. The outcome shows that there is positive correlation between geographical proximity and synergetic innovation relation. It means that the geographic proximity is the base on the process of constructing synergetic innovation network. Meanwhile, it shows the negative correlation between recognition proximity and synergetic innovation network. It shows that the start-up enterprises prefer to cooperate with the partner who has the different knowledge background.