Trust mechanisms and punishment mechanisms were important factors affecting on the exchange efficiency of knowledge networks. Most studies discussed Trust mechanisms or mechanisms separately, can not fully reflect the matching between two types of mechanisms in knowledge exchange network. By constructing a simulation model of a two-phase eight-class knowledge-sharing network and analyzing comprehensively the two mechanisms for the knowledge exchange networks in different stages. We found, ① In the early stages of the exchange of knowledge, the short-term knowledge exchange efficiency of the temporary task-based knowledge network with high initial trust mechanism and high short-term punishment mechanism is the highest, the short-term knowledge exchange efficiency of the temporary team knowledge network with low initial trust mechanism and low short-term punishment mechanism is the lowest, the short-term knowledge exchange efficiency of the temporary task-based knowledge network rapidly increase, then gradually flat, other short-term knowledge exchange efficiency is showing first declined, then gradually flat; high initial trust mechanism is more important than high short-term punishment mechanism.②In the development stages of the exchange of knowledge, the long-term knowledge exchange efficiency of the fragile emotional knowledge network with high sustained trust mechanism and high long-term punishment mechanism was the highest, the long-term knowledge exchange efficiency of the Strong transactional knowledge network with low sustained trust mechanism and low long-term punishment mechanism was the lowest, the long-term knowledge exchange efficiency of the fragile emotional knowledge network will continue to increase, other long-term knowledge exchange efficiency will be gradually reduced; high long-term punishment mechanism is more important than high sustained trust mechanism.③ the whole knowledge network structure had played an important role in the above-mentioned different trust and punishment mechanism to match. The study avoids the conventional analysis fragmented trust and punishment mechanism of one-sidedness, to make up for the lack of discussion of past deficiencies dynamic process stages, from short-term and long-term trust and punishment mechanism to show the dynamic matching knowledge network and exchange efficiency of the whole picture, to improve Different stages of knowledge networks provided important management inspiration.