Based on the perspective of social network, this paper focuses on the relationship between tie strength and effectiveness of knowledge transfer, and explores the mediating effect of organizational learning style from knowledge recipient. In addition, we also study the moderating role of knowledge codifiability from knowledge source and knowledge base compatibility between two sides in the cooperation. Then we explore the relationships using data from 305 Chinese manufacturing and high-technology firms, and analyze the data by AMOS and SPSS. The findings show that tie strength contributes positively to effectiveness of knowledge transfer. Tie strength has an indirect, positive relationship, via exploitation learning, with effectiveness of knowledge transfer. Another finding is that knowledge base compatibility has strengthened the positive relationship between tie strength and effectiveness of knowledge transfer.