Logistics platform technology innovation system and operational mode innovation system both are complex open system and have important influence over sustainable development of logistics platform enterprises. In this paper, dissipative structure theory and entropy theory are used to study the entropy change of logistics platform technology innovation system and operational model innovation system .The synergy and innovation mechanism was discussed and the entropy change model of logistics platform technology and operational mode was build. Also, the paper analysis the entropy change of Minnesota Nestivo company. Using entropy change model not only can we know about the current operating status of logistics platform technology innovation system, but also provides theoretical guidance for future innovative activities of logistics platform enterprise.