The influence of university-industry Collaboration on research performance of universities and the moderating effect of university type were empirically examined using 2007-2014 panel data of 88 universities in China, with the Sys-GMM model. It was found that: (1) The intensity of UIC had an inverted U-shape effect on the research performance of universities; (2) The university type had a negative moderating effect on the relationship between UIC and research performance of universities. This paper enriched the theory of CEEUSRO. Moreover, the theoretical reference for universities to make UIC policies was provided.