The development of information technology makes it possible for enterprises to capture large amounts of data from multiple sources. As a new capital, Big Data is an important element for enterprise to gain competitive advantage. There is limited systematic discussion on how big data affects the existing innovation management theory and enterprise's innovation management practice. Combining literature review and case study with the characteristics of big data, this paper puts forward the conceptual framework of the influence of big data on innovation management paradigm from the pattern of innovation, participants of innovation process, innovation strategy and innovation organization. The results showed that the innovation management will have a tendency of iterative innovation, platform strategy and user participation, which provides the thinking and reference for enterprise innovation practice in Big Data era.