High-tech Research Institute (HTRI) acts as a major player in high-tech R&D and commercialization, and helps to tackle core technology constraints. Classification management and classification reform is beneficial for HTRI to complete their mission. How HTRI interacts with external partners, satisfies government and market demand, selects research fields directly influences their R&D model. Based on above dimensions, we derivate three types of R&D model namely integrated model, contract model and platform model, and formulate a typology of HTRI R&D model. We conduct cases validation and capture more details based on investigation of CIOMP, SIAT and SINANO. We provide policy suggestions for HTRI reform and development from aspects including government and market join forces, enhance talent mobility, improve evaluation standard, and construct regional platform.