Based on the economic theory, such as factor endowment matching theory, structure theoretical analysis framework of technology progress path selection about coupling industry characteristics and regional factor endowment structure. Theoretically, single static technology progress path, dynamic technology progress path and R&D can achieve long-term stable economic growth increasingly in turn. Taking equipment manufacturing industry in China for research objects, our paper used the technology progress path selection model constructed by the modified production function to empirical research the different technical selection mode on technology progress; empirical research the industry characteristics and regional factor endowment structure effects on different technology selection model. The results showed that, the main source of technological progress is foreign technology introduction and imitation and foreign direct investment and imitation; domestic technology introduction and imitation and R&D have significant negative effects; industry characteristics and factor endowment structure can affect different technology selection mode, and having regional differences.