Abstract: Intellectual property capability is an important driving forces of enterprise growth which is affected by firm internal & external factors of them. , The strategical orientation is most important affecting factor for intellectual property capability. This paper discusses the relationship between market orientation, entrepreneurial orientation, i.e., the two sub dimensions of strategical orientation and the evolution of intellectual property capability respectively based on the perspective of strategic orientation. We have selected 28 enterprises in computer application industry lasted at Shanghai & Shenzhen stock exchange market at least 10 years as study samples. Scatter plots and multiple regression methods are used to analysis the evolution path of intellectual property capability. We get the result that there is a significant correlation between strategic orientation and the evolution of intellectual property capability, i.e. entrepreneurial orientation has a positive effects to the enterprises capability of intellectual property creation and application. Market orientation has a positive effects to the enterprises capability of application. Therefore, the evolution of the intellectual property capability structure is following the adjustment of enterprise’s strategic orientation, different strategic orientation would form related intellectual property capability structure.