Technology innovation network management is to maintain stability and promote the network knowledge information in the smooth running of the core problem,but the existing literature on the study of the core governance mechanism and application situation affect the relative lack of path. With members of the cooperative innovation of cultural heterogeneity as regulating variable, and study the contract relationship between governance and management of network cooperation inhibition of opportunistic behavior, and culture can be divided into individualism - collectivism and two dimension of uncertainty avoidance. Results show that the individualism and low uncertainty avoidance cultures contract governance more effective, collectivism and high uncertainty avoidance cultures relationship governance more effective, and individualism - collective dimension to contract and relationship governance interaction exists. Through the study of this article to help members of the network according to the different cultural context using more effective governance mechanism, to the different cultural innovation network member governance mechanism selection, promote enterprise's sustainable innovation ability and competitive advantage to provide theoretical support.