[Abstract] Through a statistics and analysis of Tsinghua University authorized patents in 2011-2013 and the public patents over the years in the United States, this article summarized 4 characteristics of the patents of Tsinghua University in the United States which is in the composition of authorized patents, the nature of cooperative enterprises, the growth speed of patents over the years, and the advantages of the patents technical fields. Combined with the situations of domestic high school patents in the United States and PCT international patent applications, this article pointed out the prevalent problems on the small numbers in the United States Patents and PCT applications. The study raised that the successful experience of Tsinghua University should be learned by the domestic high schools, and the domestic high schools should have the patent strategies to perfect the mechanism of patent protection, tap their own scientific research characteristics, combine with the technology demands of enterprises, speed up the layout of the overseas patents.