In total patent licensing as the main indicator, based on provincial spatial unit, using the coefficient of variation, space Markov chains and spatial autocorrelation and other methods, from the time, space and time and space to explore the 1985-2013 regional perspective of regional innovation difference between evolution and dynamic characteristics. The study found：(1) Differences of Regional Innovation presented the situation as a whole continues to expand, and presents two high-level and low-level convergence space club; (2) the transfer of regional innovation gap with the type of space is closely related to the level of innovation, the smaller the gap between regional innovation level, the greater the probability of occurrence of metastasis; vice versa. (3) The level of innovation neighborhood differences significantly affects the evolution of regional innovation, but this effect exists asymmetry. Finally, The development of regional innovation policy recommendations on this basis.