Leading industry as a driving wheel of economic development in the country or region of the evolution of national and regional economies in the industrial structure has a guiding role. This paper selects the two recent establishment in Fujian in 2007-2012, put some statistical data output tables provided by the system, use input-output coefficients of all relevant technical computing, build the evaluation system to select the leading industry, calculate the coefficient of variation for each evaluation method using weights, and calculate the total scores for each industry sector and ranking, so as to elect the leading industry in Fujian Province.