Abstract: With the increasingly enhancing the fluidity of resources and knowledge, a staged breakthrough from inside enterprises independent R&D to cooperative innovation is stridden over in the global biopharmaceutical industry, and innovative network becomes the main organization form in R&D for the new medicine. However, the generation and evolution law of biopharmaceutical innovative network still need to the further researched. By taking Zhangjiang in Shanghai as an example, the evolution law of biopharmaceutical innovative network has been analyzed from two dimensions of cooperative innovation and collaborative learning. The result shows that cooperative innovation is the inner drive for the development of biopharmaceutical innovative network; collaborative learning accelerates the structural expansion of innovative network.With the change in geographical spatial openness and cooperative flatness, biopharmaceutical innovation network goes through the evolution of inner-enterprise innovation network, local innovation network, and global innovation networks.

Key words: biopharmaceutical innovation network, evolution law, Zhangjiang