Abstract: Entrepreneurial motivation, opportunities and resources are important factors in the entrepreneurship process. But the research on the relationship among them is seldom if ever. Here, the entrepreneurial motivation is divided into two types:active or passive motivation; entrepreneurial opportunity is also divided into two types: innovative or equilibrium opportunity. Technology, financial capital, and human capital are important resources for the high-tech entrepreneurship. Therefore three kinds of initial resource driving models are defined: technology driving, financial capital driving, and human capital driving model. The associations between entrepreneurial motivation, opportunity, and resource in China are examined. Data used in this research come from interviews and valid questionnaires of 371 entrepreneurs of high-tech start ups in Changchun city of China and an AMOS model is employed to analyze the data. Empirical results indicate that there is a close relationship among them.