Abstract： A two-period overlapping generations model of human capital accumulation for R&D with threshold effects is studied. The model gives some details about innovation convergence effects and club convergence effects in the process of regional innovation. And then, based on the convergence theory of economic growth ,the threshold regression model with panel data, and the regional innovation data in China during 1996-2006, the empirical results show that there is threshold effect for R&D human capital, that is, about equal to 93 persons per 10,000 sq km, and there are also two kinds of club convergence in China. At the same time,the threshold regression model with panel data can solve the problem that club convergence effect is endogenously determined.