Abstract: Knowledge creation is becoming more and more significant to the success of business organizations, and the applications of complexity theory are increasing in organizational science researches. Under this background, the facilitating factors for organizational knowledge creation are analyzed by applying Complex Adaptive System (CAS) theory. An ideal Organizational Knowledge Creation System(OKCS) should be a CAS. Then based on the cause of system emergence phenomenon and the origin of complexity, six factors facilitating organizational knowledge creation are summarized, that is, agent adaptation, interaction between agents, system openness, tagging, diversity, and self-organization. These factors will help further understanding the main drivers of organizational knowledge creation and providing a foundation for empirical and computational modeling research in future.