Abstract: Aiming at the exploitation and management of tacit knowledge， a theoretical model about the relationship between tacit knowledge communication， tacit knowledge transfer, and tech-innovation is bullt up; and 12 hypotheises on the basis of theoretical analysis is put forward. In order to examine the model and hypotheses， the method of questionnaire is adopted and then the data of 255 valid formal questionnaires from part of manufacturing enterprises and institutes both in west and east areas are put into the Structural Equation Model(SEM) by use of the AMOS 5.0 software. Finally, according to the results, the related advices are brought forward.