Science appraisal of scientific research talents is helpful to talented person discovery and is conduced to the talented person growth. How to appraise scientific research talents? At present, it is still does not have the unified method. The medical talent is taken as an example. Impact factor, weighted average, multi database method, Bradford law, contribute method, peer expert evaluation method are combined with. Starting from the main scientific research activities, such as scientific research talents paper, cited paper, scientific research achievement, technological award, monograph, invention patent, bearing scientific research project, academic position, new medicine research and development, and so on, the quantitative evaluation talented person formula and target are proposed. And the comprehensive appraisal pattern for the influential power of scientific research talent is initially constructed.