Abstract: S&T polices play a critical role in the constitution of National Innovation System(NIS) and promotion of independent innovation. However, most researches on S&T policies dwell on the descriptive analysis .It is rare to see the quantified research. As a result, it is difficult to evaluate accurately the effect of S&T polices on the technological and economic performance. The S&T polices is tried to quantify. Chinese S&T polices are objectively evaluated by typical econometric models. S&T polices issued by national departments from 1978 to 2006 are collected and a database is built. Among them, 423 S&T policies, most related with innovation, are selected from the database. And then, these polices are quantified and the evolution of Chinese S&T polices is described since 1978. It is found that the coordination of different departments on different policy goals has significant phased. With the high attention paying to S&T policies, the coordination among policies increases rapidly. The reason is that the institutional path dependence and the competition of benefits among different departments have aggravated an unbalanced distribution of the right to influence technology policies during the process of reform. A method introducing policy variable to C-D function is explored and the effect of S&T polices on the performance is discussed. Moreover, the effect of coordination among departments of policy goals on technological and economic performance is discussed.