As a new kind of network organization, the cluster supply chain holds a unique advantage in the mass customization. The theories of the mass customization in the cluster supply chain are described in detail, including the basic structure, driving mechanism and operational flow. Finally, by citing the Jinjiang shoemaking industrial cluster, a conclusion can be drawn again, that is, the mass customization in the cluster supply chain can provide flexible, fast and inexpensive customizing products or service, and improve the competitiveness of the industrial cluster ultimately.