作为一种平衡利润增长需求和社会价值诉求的新兴创新范式，负责任创新已被越来越多的企业视为其积极承担社会责任并实现可持续发展目标的有效路径。鉴于当前以科技创新助力农业可持续发展的广泛呼吁，探讨农业领域负责任创新议题极为必要。本研究基于资源编排理论，构建了绿色创业导向影响企业负责任创新的研究模型。采用层次回归和MEDCURVE宏程序对来自248家农业企业的两时点调研数据进行分析，实证结果表明：（1）绿色创业导向对绿色供应链整合有正向影响；（2）绿色供应链整合对企业负责任创新有倒U型影响；（3）绿色供应链整合在绿色创业导向与企业负责任创新间发挥中介作用；（4）大数据分析能力正向调节绿色创业导向对绿色供应链整合的线性关系，以及绿色供应链整合与企业负责任创新间的倒U型关系。本研究不仅丰富了企业负责任创新的形成机制研究，也为企业管理者和政策制定者推动企业负责任创新提供实践启示。

   As an emerging innovation paradigm that balances the demand for profit growth and social value, responsible innovation has been increasingly recognized by enterprises as an effective approach for them to proactively assume social responsibilities and achieve sustainable development goals. In view of the widespread appeal to promote the sustainable development of agriculture with scientific and technological innovation, it is extremely necessary to discuss the topic of responsible innovation in agriculture. Based on the resource orchestration theory, this study constructed a theoretical model that explores how green entrepreneurial orientation influences enterprise responsible innovation. The research data from 248 agricultural enterprises were analyzed using the hierarchical regression and MEDCURVE macro-program. The empirical results indicated that: (1) green entrepreneurial orientation positively influences green supply chain integration; (2) green supply chain integration, in turn, has an inverted U-shaped influence on enterprise responsible innovation; (3) green supply chain integration acts as a mediator between green entrepreneurial orientation and enterprise responsible innovation; and (4) big data analytics capability positively moderates the linear relationship between green entrepreneurial orientation and green supply chain integration, as well as the inverted U-shaped relationship between green supply chain integration and enterprise responsible innovation. This study has not only enriched the research on the formation mechanism of enterprise responsible innovation, but also provided practical enlightenment for managers and policy makers to promote enterprise responsible innovation.