本文关注的核心问题是：如何以用户需求为导向，构建有效的产学研用协同创新的模式和机制？围绕这一问题，桥接了资源依赖、模块化理论和协同创新理论，分析了在资源依赖和模块化的交叉调节下对于产学研用协同创新的影响关系。在此基础上，研究设计基于模块化的产学研用协同创新网络组织模型和模块化协调机制。结合案例验证发现：（1）在以模块为交互载体的产学研用协同创新网络组织中，资源依赖能够促进产学研各方的合作创新，而模块化既能改善资源过度依赖问题，还能担当创新需求方与供给侧的整合者；（2）模块化可以有效促进需求分析?模块创新?资源配置?组织协同的过渡，且利于确立产学研用协同创新重点和策略；（3）基于模块化的协调机制（规范性约束机制、延续性交互机制和架构调节机制），有利于促进企业、大学、科研院所等创新主体之间知识交互和知识创新，有利于推动产学研用协同创新网络组织的持续运转。

The core issue focused in this paper is: how to construct an effective industry-university-institute-user (IURU) collaboration innovation mode combining its mechanism guided by the demands of users? Around this problem, the resource dependence theory (RDT) is bridged with modularity theory and collaboration theory, and the influential relationship of the cross coordination of RFT and modularity on IURU collaboration innovation is analyzed. Moving forward, the IURU collaboration innovation organization network model featuring module as interaction carrier, is designed followed by the module-based coordination mechanism. Some conclusions are drawn after further checking with case study, which includes: (1)In the modular IURU collaboration innovation organization network, RDT is able to facilitate the cooperative innovation among multiple stakeholders. Meanwhile, modularity may not only alleviate the excessive dependence of external resources, but acts as the integrator between innovation demand side and supply side; (2) modularity can be adopted to promote users’ requirements analysis?module innovation?resource configuration?organization collaboration, and it is also useful for defining the IURU collaboration innovation focus and strategy; (3) the module-based coordination mechanism (formal constraint mechanism, continuous interaction mechanism and modular product architecture (MPA) coordination mechanism) is helpful for enhancing the knowledge interaction and knowledge innovation among enterprise, university, institute, etc. which is also useful for promoting the sustainable operation of IURU collaboration innovation organization network.