文章从知识资源与企业创新的关系入手，引入创业导向作为中介变量，政治网络和竞争强度作为调节变量，建立了知识资源、创业导向、政治网络、竞争强度和企业创新之间的理论模型。以148家企业的数据为样本进行层级回归分析，得出结论：（1）知识资源与创业导向呈正向相关；（2）创业导向与企业创新呈正向相关；（3）创业导向在知识资源与企业创新的关系中起中介作用；（4）知识资源、政治网络和竞争强度之间的交互对于创业导向具有显著的正向影响。

This article mainly investigates the relationship between the knowledge resources and enterprise innovation, analyzes the mediating influence of the entrepreneurial orientation and the moderating effect of the political networking and the competitive intensity in the relationship above. It sets up a theoretical model about knowledge resources, entrepreneurial orientation, political networks, competitive intensity and the enterprise innovation. Based on the sample of 148 firms, we found that: Firstly, knowledge resources has a positive effect on entrepreneurial orientation. Secondly, entrepreneurial orientation has a positive effect on enterprise innovation. Thirdly, entrepreneurial orientation plays a mediating role between knowledge resources and enterprise innovation. Finally, the interaction among knowledge resources, political networking and competitive intensity has a positive influence on entrepreneurial orientation.