主动性与员工创新行为的关系是创新微观研究的热点，已有研究均未探讨其作用机制。文章基于认知-动机理论，以中国医药生物技术企业247名员工为被试样本，对员工创新行为（EIB）、主动性人格（PP）、创新自我效能感（ISE）、创新结果预期（IOE）4个变量进行了实证研究，探究了主动性人格影响员工创新行为的作用机制。研究发现，以上4个变量之间呈显著相关性，PP通过ISE和IOE的多重中介效应间接影响员工创新行为。

The relationship between proactivity and employee innovative behavior has always been a hot topic in the field of innovation microscopic research. However, the studies have ignored the mechanism. Based on cognitive - motivation theory, the paper discusses the mechanism of proactive personality and employee innovative behavior . An empirical research is conducted with effective data of 247 employees from pharmaceutical biotech companies of China, exploring the relaionships of employee innovative behavior (EIB), proactive personality (PP), innovative self-efficacy (ISE), innovative outcome-expectation ( IOE). The results show that there are significant correlations between the above variables,and PP indirectly affects employee innovative behavior via multiple mediating of ISE and IOE.