“纳米-生物”会聚技术的测度及启示

摘要/Abstract

摘要： 运用专利计量与信息可视化技术手段,对会聚技术进行测度与可视化分析,是一个较新的研究课题。对纳米-生物(NB)会聚技术测度与可视化分析的结果显示,2000-2009年间,NB会聚技术呈现出快速发展的势头;NB会聚技术共涉及到4 998个不同的技术小类,其中"细菌、真菌、病毒等的测试与探测技术"是最重要的领域;NB会聚技术的热点主题,主要集中在核酸、碳纳米管、制备方法、生物标本、癌症治疗、靶标分子等方面。中国政府和科学技术界,应通过加强纳米与生物技术领域的合作,拓展纳米与生物技术的合作领域和合作主题,培养更多的NB会聚技术领域人才等途径,推动中国NB会聚技术的不断发展。NB会聚技术的测度与可视化分析方法,可应用于其他会聚技术领域。

关键词: 会聚技术, NBIC, 测度, 可视化, 热点技术领域, 热点技术主题, CiteSpace

Abstract: It is a new research subject that measures and visualizes (NANO-BIO-INFO-COGN) NBIC converging technologies via patentometric and information visualization techniques. The results of measuring and visualizing of (NANO-BIO) NB converging technology indicates that NB converging technology demonstrates an upsurging trend during the period of 2000-2009; NB converging technology involves total 4,998 different sub-technology classifications, and focuses on test and detection of bacteria, fungi, and viruses; the hot topics of NB technology are nucleic acid/nucleic acids, carbon nanotube/carbon nanotubes, preparation method, biological sample, cancer treatment, target molecule, etc. Chinese government and S&T community should take measures to strengthen the collaboration between nano-biotechnology fields in order to expand the collaborative fields and topics, to cultivate more NB researchers, and to promote NB converging technology in China. The methodology of measuring and visualizing NB converging technology in here could be applied to other fields of converging technologies.

Key words: converging technology, NBIC, measurement, visualization, hot technology field, hot technology topic, CiteSpace

中图分类号:

C931.2

栾春娟. “纳米-生物”会聚技术的测度及启示[J]. 科研管理, 2012, 33(7): 48-58.

Luan Chunjuan. Measuring and visualizing Nano-Bio converging technologies and its enlightenment[J]. Science Research Management, 2012, 33(7): 48-58.

参考文献

[1] 张宁,罗长坤. "会聚技术"及其对科技管理的影响[J]. 研究与发展管理,2005,17(5):97-100.
[2] National Science Foundation Mihail C. Roco and William Sims Bainbridge. Converging Technologies for Improving HumanPerformance-nanotechnology,biotechnology, information technology and cognitive science .Arlington, Virginia :2002.
[3] 穆荣平. 中国战略性新兴产业的选择 .大连:2010.
[4] McLeish C,Nightingale P. Biosecurity, bioterrorism and the governance of science: The increasing convergence of science and security policy[J]. Research Policy,2007,36(10):1635-1654.
[5] Wolbring G. Why NBIC? Why human performance enhancement[J]? Innovation-the European Journal of Social Science Research,2008,21(1):25-40.
[6] Loveridge D,Dewick P,Randles S. Converging technologies at the nanoscale: The making of a new world[J]? Technology Analysis & Strategic Management,2008,20(1):29-43.
[7] Schmidt J. C. Tracing interdisciplinarity of converging technologies at the nanoscale: A critical analysis of recent nanotechnosciences[J]. Technology Analysis & Strategic Management,2008,20(1):45-63.
[8] Roco M. C. Progress in governance of converging technologies integrated from the nanoscale, in Progress in Convergence: Technologies for Human Wellbeing[M],W.S.R.M.C. Bainbridge,Editor.2006,Blackwell Publishing:Oxford.1-23.
[9] Roco M. C,Bainbridge W. S. Converging technologies for improving human performance: Integrating from the nanoscale[J]. Journal of Nanoparticle Research,2002,4(4):281-295.
[10] Staples M,Daniel K,Cima M. J,et al. Application of micro- and nano-electromechanical devices to drug delivery[J]. Pharmaceutical Research,2006,23(5):847-863.
[11] 何敏. 论"实用广义技术测度模式"的局限性[J]. 科学管理研究,1984,(02):52-55.
[12] 李国祥,徐景德,王明龙,刘茂家,吴继华. 足球运动员射门技术测度方法的研究[J]. 大连理工大学学报,1995,(03).
[13] 张宏斌,牛赟. 基于3S技术测度祁连山水源林可持续经营指标的构想[J]. 防护林科技,2005(5):46-48.
[14] 王艳平,尹怀宁. 应用AHP修正技术测度居民环境感受的研究[J]. 辽宁师范大学学报(自然科学版),1994(1).
[15] Altynbekov Z. O,Gorobtsov V. M,Nikitin G. M,et al. technological measures for reducing and localizing dust and gas emission in blast-furnaces[J]. Industrial Laboratory,1992,58(7):675-677.
[16] Shishkin A. Y. A statistically planned experiment as a method of designing the parameters at technological measurements[J]. Measurement Techniques,2007,50(2):119-124.
[17] Hogan M. D,Carnahan L. J,Carpenter R. J,et al. Information technology measurement and testing activities at NIST[J]. Journal of Research of the National Institute of Standards and Technology,2001,106(1):341-370.
[18] 武夷山. 科学技术测度体系(译著节选)·武夷山的博客 ·科学网 .2010. http://www. sciencenet.cn/m/user_content.aspx?id=19651.2010-08-16.
[19] 王贤文. 基于专利共被引的企业技术发展与技术竞争分析:以世界500强中的工业企业为例. 科学管理研究,2010,4(2):19-25.
[20] 栾春娟,王续琨,刘则渊,侯海燕. 专利计量研究国际前沿的计量分析. 科学学研究,2008(2):334-338,310.
[21] 栾春娟. 专利文献计量分析与专利发展模式研究 (博士学位论文).大连:大连理工大学,2008.
[22] Guan J. C,He Y. Patent-bibliometric analysis on the Chinese science - technology linkages[J]. Scientometrics,2007,72(3):403-425.
[23] Dalpe R. Bibliometric analysis of biotechnology[J]. Scientometrics,2002,55(2):189-213.
[24] Bartkowski A,Gora Z,Schramm R. Patentometric analysis using linked online databases[J]. Nfd Information-Wissenschaft Und Praxis,2001,52(5):293-299.
[25] Leydesdorff L. the generation of aggregated journal-journal citation maps on the basis of the cd-rom version of the science-citation-index[J]. Scientometrics,1994,31(1):59-84.
[26] H. Small,E. Sweeney,E. Greenlee. CLUSTERING THE SCIENCE CITATION INDEX USING CO-CITATIONS .2. MAPPING SCIENCE. Scientometrics,1985,8(5-6):321-340.
[27] Tijssen R. J. W,Vanleeuwen T. N. on generalizing scientometric journal mapping beyond isis journal and citation databases[J]. Scientometrics,1995,33(1):93-116.
[28] Chen C. M,Paul R. J,O'Keefe B. Fitting the jigsaw of citation: Information visualization in domain analysis[J]. Journal of the American Society for Information Science and Technology,2001,52(4):315-330.
[29] McCain K. W,Verner J. M,Hislop G. W,et al. The use of bibliometric and Knowledge Elicitation techniques to map a knowledge domain: Software Engineering in the 1990s[J]. Scientometrics,2005,65(1):131-144.
[30] Leydesdorff L. Mapping interdisciplinarity at the interfaces between the science citation index and the social science citation index[J]. Scientometrics,2007,71(3):391-405.
[31] Zou F,Wu M. X,Wu K. L. Outcomes associated with ophthalmology, optometry and visual science literature in the Science Citation Index from mainland China, 2000-2007[J]. Scientometrics,2009,81(3):671-682.
[32] Van Den Besselaar P,Heimeriks G. Mapping research topics using word-reference co-occurrences: A method and an exploratory case study[J]. Scientometrics,2006,68(3):377-393.
[33] Zhang J,Wolfram D,Wang P. L,et al. Visualization of health-subject analysis based on query term co-occurrences. Journal of the American Society for Information Science and Technology,2008,59(12):1933-1947.
[34] 栾春娟. 基于专利计量与可视化手段的技术前沿探测——以波音公司为例[J]. 情报理论与实践,2009(8):68-71.
[35] Bhattacharya S. Mapping inventive activity and technological change through patent analysis: A case study of India and China[J]. Scientometrics,2004,61(3):361-381.
[36] Lee S,Seol H,Park Y. Using patent information for designing new product and technology: keyword based technology roadmapping[J]. R & D Management,2008,38(2):169-188.
[37] Chen C. M,Kuljis J. The rising landscape: A visual exploration of superstring revolutions in physics[J]. Journal of the American Society for Information Science and Technology,2003,54(5):435-446.
[38] Chen C. M. CiteSpace II: Detecting and visualizing emerging trends and transient patterns in scientific literature[J]. Journal of the American Society for Information Science and Technology,2006,57(3):359-377.
[39] Chen C. M,Song I. Y,Yuan X. J,et al. The thematic and citation landscape of Data and Knowledge Engineering (1985-2007) [J]. Data & Knowledge Engineering,2008,67(2):234-259.
[40] Onyancha O. B. Growth, productivity, and scientific impact of sources of HIV/AIDS research information, with a focus on eastern and southern Africa[J]. Ajar-African Journal of Aids Research,2008,7(1):55-70.
[41] Pinto A. L,Barquin B. A. R,J. Gonzalez A. M,et al. Analysis of the Social Network in Serial Publications: representation in the Journal of Documentation[J]. Investigacion Bibliotecologica,2009,23(48):13-32.
[42] Chen Q,Li D. Y,Shitaka Y,et al. Behaviors of Microtubules (MTs) Driven by Biological Motors (Dynein c) at Collisions Against Micro-Fabricated Tracks and MTs for Potential Nano-Bio-Machines[J]. Journal of Nanoscience and Nanotechnology,2009,9(9):5123-5133.
[43] Jokerst J. V,Raamanathan A,Christodoulides N,et al. Nano-bio-chips for high performance multiplexed protein detection: Determinations of cancer biomarkers in serum and saliva using quantum dot bioconjugate labels[J]. Biosensors & Bioelectronics,2009,24(12):3622-3629.
[44] Torimitsu K. Nano-bio science-unification of neural functions with nanotechnology[J]. Electrochemistry,2003,71(9):809-813.
[45] Shim Y. B,Biosensor used for detecting biomolecule, e.g. DNA, obtained by fixing conducting polymer, dendrimer, gold nanoparticle, probe, biomolecule, biotin indicator probe, and avidin indicator hydrazine to electrode surface ,Univ Pusan Nat Ind Coop Found (Uypu).
[46] Bianco A,Pantarotto D,Prato M,New functionalized carbon nanotube useful e.g. to prepare an immunogenic composition, treat/prevent cancer, autoimmune and infectious diseases, and to prepare electrochemical biosensors .2005.
[47] Hong J. C.,Huh C,Kim K. H,et al,New silicon biosensor, used in many applications, e.g. environments, foods, the military, industry, and diagnosis of a disease, comprises light emitting layer or a self-emitting reaction unit-emitting light .2008.
[48] Gouma P,Biosensing material comprising polymer-enzyme nanocomposite fibers retaining enzyme activity, useful e.g. in biosensors, artificial kidneys, and removal of urea from alcoholic beverages and wastewater .2005.
[49] Baik Y. J,Hwang G. W,Jeong J,et al,Biosensor device for detecting DNA molecule, proteins, antibody or antigen material, comprises gate electrode, formed with diamond thin film for controlling switch operation and metal-oxide-semiconductor field-effect transistor board .2008.
[50] Hartmann J. X,Keating P,Measuring the susceptibility of a subject to calcifying nanoparticle formation comprises producing a cell culture, extracting aliquots from the peripheral blood mononuclear cell culture, dispensing aliquots in wells, and incubating aliquots ,Univ Florida Atlantic (Uyfl),2009.
[51] 米黑尔·罗科,威廉·班布里奇编. 蔡曙山,王志栋,周允程等译. 聚合四大科技提高人类能力[M].北京:清华大学出版社,2010:213-220.
[53] 鞠思婷,朴玲钰,杨磊等. 碳纳米管与生物分子的相互作用[J]. 化学进展,2010,22(9):1767-1775.